Anastasia V. Stolyarova

A sibling study of variation in parental mutation rates

The paper identifies de novo mutations in siblings and finds no differences in mutation rates by ancestry or smoking status, but links disruptions in REV1 and LIG1 to increased germline mutation rates.

What sets the mutation rate of a cell type in an animal species?

The paper reviews patterns and theories on how natural selection shapes mutation rates in animal germline and somatic cells across species.

Mutation bias in driver genes reveals the distribution of effects of oncogenic mutations

The paper quantifies mutation bias in driver genes to estimate the number of driver mutations and their effect distribution across oncogenes and tumor-suppressor genes.

The distribution of highly deleterious variants across human ancestry groups

The paper argues that highly deleterious variants are similarly distributed across human ancestry groups and shows that loss of function alleles at constrained genes conform to mutation-drift-selection balance predictions.