Mirjana Maletić‐Savatić

The paper identifies a disrupted mitochondrial-purine metabolism link in MECP2 Duplication Syndrome across multiple models, linking it to neurodevelopmental issues.

The paper analyzes sleep data from 1527 pediatric PSGs across five sites to study neurodevelopmental disorders, identifying sleep architecture disruptions in Down Syndrome and developing a sleep stager and brain age prediction model.

NMRQNet automatically identifies and quantifies metabolites in human plasma NMR spectra, outperforming existing methods and identifying potential biomarkers for neurological disorders.

SPA-STOCSY is an automated tool for identifying annotated and non-annotated metabolites in NMR spectra, showing high accuracy and efficiency in both synthetic and real data.

PolyAMiner-Bulk identifies and decodes alternative polyadenylation dynamics from bulk RNA-seq data, revealing novel APA changes in disease contexts and Alzheimer's Disease.

This study identifies oleic acid as a ligand for TLX/NR2E1 that promotes hippocampal neurogenesis by converting TLX from a repressor to an activator of cell cycle and neurogenesis genes.