Damian W. Young

Druggable CSNK2A1-MeCP2 regulatory axis links Okur-Chung neurodevelopmental syndrome with MECP2-related disorders

The paper identifies a druggable CSNK2A1-MeCP2 regulatory axis linking Okur-Chung neurodevelopmental syndrome with MECP2-related disorders through CRISPR screens and mouse models.

SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra

SPA-STOCSY is an automated tool for identifying annotated and non-annotated metabolites in NMR spectra, showing high accuracy and efficiency in both synthetic and real data.

Oleic acid triggers hippocampal neurogenesis by binding to TLX/NR2E1

This study identifies oleic acid as a ligand for TLX/NR2E1 that promotes hippocampal neurogenesis by converting TLX from a repressor to an activator of cell cycle and neurogenesis genes.

Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying

This paper develops a multiplex hextuple luciferase assay to simultaneously assess multiple cellular pathways and demonstrates its application in monitoring pathway responses to various treatments.