Zhen Chen

This study identifies MFAP5 as a driver of elastic fiber disorganization in pulmonary fibrosis, showing its role in fibroblast activation and ECM production through TGFβ signaling.

This study identifies TXNDC5 as a key regulator of extracellular matrix homeostasis in pulmonary hypertension, showing its role in vascular remodeling and potential as a therapeutic target.

This study shows STING contributes to pulmonary hypertension by enhancing interferon signaling and suppressing BMPR2 signaling through F2RL3 regulation in endothelial cells.