Systematic morphological profiling of human gene and allele function reveals Hippo-NF-κB pathway connectivity
Mohammad Hossein Rohban, Shantanu Singh, Xiaoyun Wu, Julia Hicks‐Berthet, Mark‐Anthony Bray, Yashaswi Shrestha, Xaralabos Varelas, Jesse S. Boehm, Anne Elizabeth Carpenter
The paper uses morphological profiling to identify gene function and connectivity, revealing TRAF2/C-REL's negative regulation of Hippo pathway effectors.
eLife · Mar 18, 2017Peer-reviewedSystems Biology