Pharmacology & ToxicologybioRxivPreprint
Cytotoxic activity against human leukemia cells of Kaempferol-3-O-rhamnoside from Vietnamese Schima wallichii (DC.) Korth: A combination of in vitro and in silico insights
Manh Hung Tran, Yến Nhi Nguyễn, Thuy Mi Pham Lam…·Phu Tran Vinh Pham
This study identifies kaempferol-3-O-rhamnoside from Schima wallichii as a cytotoxic compound against leukemia cells, showing in vitro and in silico evidence of its mechanism involving caspase activation and PARP1 inhibition.
DOI 10.1101/2024.12.25.630323