Paul R. J. Birch

HFinder uses deep learning to automate and quantify analysis of plant-microbe interfaces in confocal images, enabling detailed study of subcellular interactions.

This study isolates and analyzes intracellular vesicles from Phytophthora infestans to identify vesicle-associated proteins and their potential cargo, including effectors and secretory proteins.

This study identifies PaRXLR40 as a virulence factor in Phytophthora agathidicida that suppresses host immunity by targeting the ARIA protein, promoting disease susceptibility in kauri and Nicotiana benthamiana.

This study shows the RXLR-EER motif directs RXLR effectors to an unconventional secretion pathway linked to extracellular vesicles in Phytophthora infestans.

This study identifies PiMDP1 and PiMDP2 as molecular markers for extracellular vesicles in Phytophthora infestans, revealing their association with RxLR effectors and their role in infection.

The paper shows that RXLR and EER motifs in oomycete effectors are proteolytically processed before secretion, with cleavage sites constrained to specific positions.