Mariko Isshiki

Integrating multi-omic QTLs and predictive models reveals regulatory architectures at immune-related GWAS loci in CD4+ T cells

The paper integrates multi-omic QTLs and predictive models to identify regulatory variants in CD4+ T cells and their role in immune-related GWAS loci.

High-Coverage Jomon Genomes Provide Insights into Population Structure and Genetic Traits of Ancient Japanese Hunter-Gatherers

This study analyzes eight high-coverage Jomon genomes to reveal genetic continuity and phenotypic traits of ancient Japanese hunter-gatherers, showing their genetic influence on present-day Japanese populations.

Genetic disease risks of under-represented founder populations in New York City

The paper identifies founder populations in New York City using genomic data and finds 202 likely disease-causing variants enriched in these under-represented groups, many of which are new discoveries.