New insights on malaria parasite adaptation yielded by samples archived for more than 50 years
Alfred Amambua‐Ngwa, Mouhamadou Fadel Diop, CHRIS J. DRAKELEY, Umberto D’Alessandro, Dominic P. Kwiatkowski, David J. Conway
The paper analyzes old Plasmodium falciparum genomes to study malaria parasite adaptation over 50 years, finding strong positive selection at surface protein loci and changes in allele frequencies.
bioRxiv · Mar 11, 2025 · PreprintMicrobiology