Tuning non-linear mechanics in collagen hydrogels modulates three dimensional cellular morphotypes
Marco A. Enriquez Martinez, Zhao Wang, Robert J. Ju, Petri Turunen, Jitendra P. Mata, Elliot Paul Gilbert, Ján Lauko, Samantha J. Stehbens, Alan E. Rowan
This study shows that altering the non-linear elasticity of collagen hydrogels affects cell morphology, migration, and matrix deformation through mechanical interactions with a second polymer component.
bioRxiv · Mar 18, 2024 · PreprintBiophysics