Author

Gregory P. Sevilla

Fred Hutch Cancer CenterORCID 0000-0002-6590-9413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Emily J. GirardiD· 1 shared James M. OlsoniD· 1 shared Jason Price· 1 shared Monique L. Howard· 1 shared Natalie Winblade NairniD· 1 shared Pamela Young· 1 shared Tinh-Doan Phi· 1 shared Zachary R. CrookiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioengineering

Emily J. GirardORCID

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1 paper

Recent·Most cited

BioengineeringNature CommunicationsPeer-reviewedOct 9, 2024

CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effect

Zachary R. Crook, Gregory P. Sevilla, Pamela Young…·Natalie Winblade Nairn

CYpHER is a targeted protein degradation technology that uses pH-dependent release and the transferrin receptor to deliver drugs to endolysosomes, demonstrating potency and durability in vitro and in vivo.

40 citationstop 3%

experimental assaydrug response / drug discovery

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