Author

Kaisle A. Hill

Annexon Biosciences (United States)ORCID 0000-0002-6592-7814Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aayami Jain· 1 shared Angelica Garcia· 1 shared B. Joy Quejarro· 1 shared Basem Al-ShayebiD· 1 shared Beeke WienertiD· 1 shared Brian J. SilvaiD· 1 shared Cassandra D. LalisaniD· 1 shared Craig L. EnnisiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Aayami Jain

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedMar 23, 2024

Functional Screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair

Juan A. Pérez-Bermejo, Oghene Efagene, William M. Matern…·Kristen L. Seim

The paper identifies optimized protein-based enhancers of HDR in human HSPCs through functional screening, improving HDR efficiency without increasing off-target effects.

8 citations

humanCRISPR screen

GenomicsbioRxivPreprintAug 18, 2023

Programmable multi-kilobase RNA editing using CRISPR-mediated trans-splicing

Jacob de Riba Borrajo, Kamyab Javanmardi, James Griffin…·Basem Al-Shayeb

Splice Editing uses CRISPR-mediated trans-splicing to correct large RNA segments in human cells, enabling efficient and specific RNA and protein correction without DNA mutagenesis.

21 citations

humanCRISPR screen