Author
Gladstone InstitutesORCID 0000-0001-7625-358XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Juan A. Pérez-Bermejo, Oghene Efagene, William M. Matern…·Kristen L. Seim
The paper identifies optimized protein-based enhancers of HDR in human HSPCs through functional screening, improving HDR efficiency without increasing off-target effects.
Juan A. Pérez-Bermejo, Luke M. Judge, Christina L Jensen…·Bruce R. Conklin
This study investigates the functional impact of a BAG3 allele associated with reduced heart failure risk, showing it enhances cardiomyocyte stress resistance through altered protein interactions.
Ian A. Mellis, Hailey I. Edelstein, Rachel Truitt…·Arjun Raj
The paper identifies transcription factors that maintain cell identity by analyzing their responsiveness to perturbations in human iPSC-derived cardiac myocytes and fibroblasts.
Arun Padmanabhan, Michael Alexanian, Ricardo Linares-Saldana…·Deepak Srivastava
This study identifies a BRD4-GATA4 interaction that regulates mitochondrial homeostasis in adult cardiomyocytes by modulating gene expression related to energy production.