Santiago Jaramillo

Modulation of metastable ensemble dynamics explains the inverted-U relationship between tone discriminability and arousal in auditory cortex

A multimodal approach for visualization and identification of electrophysiological cell types in vivo

This paper introduces PhysMAP, a framework that uses multimodal electrophysiological data to identify and study cell types in vivo, showing improved alignment with transcriptomic cell types and circuit dynamics.

The serotonergic psychedelic DOI impairs deviance detection in the auditory cortex

This study shows that DOI, a serotonergic psychedelic, increases neural response variability and impairs deviance detection in the auditory cortex of mice by reducing sensitivity to unexpected sounds.

PhysMAP - interpretable in vivo neuronal cell type identification using multi-modal analysis of electrophysiological data

PhysMAP identifies neuronal cell types from electrophysiological data by integrating multiple modalities, outperforming single-modal approaches in mouse brain recordings.

Decision-making dynamics are predicted by arousal and uninstructed movements

The paper shows that mice's decision-making states during tasks can be predicted by arousal and uninstructed movements.

Selectivity to acoustic features of human speech in the auditory cortex of the mouse

The paper shows that mice can learn to categorize speech sounds based on formant transitions and voice onset time, with selectivity for these features in specific auditory cortical regions.

Passive exposure to task-relevant stimuli enhances categorization learning

The paper shows that passive exposure to task-relevant stimuli improves learning speed in mice and is effectively modeled by neural networks using unsupervised learning during exposure.

Sound-evoked responses of distinct neuron classes from the tail of the striatum

The paper compares sound-evoked responses of D1-expressing direct-pathway neurons and their neighbors in the posterior striatum of naive mice, finding similar frequency tuning and amplitude modulation encoding.

Contributions of distinct auditory cortical inhibitory neuron types to the detection of sounds in background noise

This study shows that inhibitory neurons in the auditory cortex are crucial for detecting sounds in noisy environments.

Response outcomes gate the impact of expectations on perceptual decisions

The paper shows that rats adjust their decision biases based on previous outcomes, using a model where reward signals gate the influence of expectations on decisions.

Stable representation of sounds in the posterior striatum during flexible auditory decisions

This study investigates the role of posterior striatal neurons in auditory decisions in mice, finding they encode sound features and influence choices without directly controlling movement.