Author

Natalie L. Dawson

Institute of Structural and Molecular BiologyORCID 0000-0002-6607-9976Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1

Frequent Co-Authors

Christine Anne OrengoiD· 2 shared Jonathan Gill LeesiD· 2 shared Aurelio A. Moya‐GarcíaiD· 1 shared Camilla PangiD· 1 shared Clemens RaueriD· 1 shared Felix Alexander KrügeriD· 1 shared Franca FraternaliiD· 1 shared Harry M. ScholesiD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Christine Anne OrengoORCID

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2 papers

Recent·Most cited

SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals

Su Datt Lam, Nicola Bordin, Vaishali Waman, Harry M. Scholes, Paul Ashford, Neeladri Sen, Lucy van Dorp, Clemens Rauer, Natalie L. Dawson, Camilla Pang, Mahnaz Abbasian, Ian Sillitoe, Sarah Edwards, Franca Fraternali, Jonathan Gill Lees, , Christine Anne Orengo

The paper predicts SARS-CoV-2 spike protein interactions with ACE2 orthologues across 215 vertebrates, finds mutations in ACE2 are more detrimental, and shows human strains are present in animals.

Scientific Reports · Oct 5, 2020Peer-reviewedBioinformatics

Structural and Functional View of Polypharmacology

Aurelio A. Moya‐García, Tolulope Tosin Adeyelu, Felix Alexander Krüger, Natalie L. Dawson, Jonathan Gill Lees, John P. Overington, Christine Anne Orengo, Juan A. G. Ranea

This study links polypharmacological drugs to CATH functional families, showing their network properties relate to drug side effects and target identification.

Scientific Reports · Aug 24, 2017Peer-reviewedBioinformatics