Glenn David Wadley

Molecular responsiveness to testosterone is uncoupled from skeletal muscle mass and strength in males aged 18 - 80 years

This study shows that free testosterone is linked to skeletal muscle transcriptome changes but not to muscle mass or strength in males aged 18-80.

MetAR: A semi-automated meta-analysis of skeletal muscle androgen receptors association with age

This study uses a novel R-based pipeline, MetAR, to analyze RNA-seq datasets and finds that androgen receptor expression declines with age in human skeletal muscle.

Mitochondria isolated from male skeletal muscle contain a distinct 1 population of miRNA that are differentially expressed following acute exercise

The paper profiles miRNA in human skeletal muscle mitochondria before and after acute exercise, finding a distinct miRNA population with hsa-miR-146b-3p differentially expressed post-exercise.

Skeletal muscle mitochondria contain nuclear-encoded RNA species prior to and following adaptation to exercise training in rats

This study identifies nuclear-encoded RNAs in mitochondria of rat skeletal muscle, with some miRNAs showing altered abundance after exercise training.

Total testosterone is not associated with muscle mass, function or exercise adaptations in pre-menopausal females

This study finds that total testosterone is not linked to muscle mass or strength in pre-menopausal females, but bioavailable testosterone and nuclear-localized androgen receptor are associated with muscle hypertrophy.