Sarah E. Alexander

This paper develops and validates a SEC-SAX protocol for enriching extracellular vesicles from small plasma volumes for quantitative proteomics in human and mouse samples.

This study finds that total testosterone is not linked to muscle mass or strength in pre-menopausal females, but bioavailable testosterone and nuclear-localized androgen receptor are associated with muscle hypertrophy.

This study integrates multi-OMIC data from 12 cohorts to identify exercise-specific molecular signatures and gene regulatory patterns in human skeletal muscle.

This study examines how sleep restriction and resistance exercise interact to affect skeletal muscle transcriptomics in young females, finding that sleep loss moderates the gene expression response to exercise.

This study shows that ACTN3 genotype affects androgen response in skeletal muscle by altering AR expression and pathways related to muscle homeostasis.

The paper compares alternative polyadenylation in primary human myoblasts and C2C12 cells during differentiation, finding less alternative polyadenylation in human cells.