Hannah-Ruth Engelbrecht

The paper investigates how DNA methylation in peripheral blood relates to immune cell type composition in the frontal brain using epigenome-wide association studies and machine learning.

This study examines differences between Infinium MethylationEPIC v1 and v2, showing high array-level concordance but probe-level variation, and recommends accounting for version differences in analyses.

The paper identifies genetic loci associated with human cortical structure and finds genetic correlations with neuropsychiatric disorders.