Aaron L. Goldman

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

The paper conducts GWAS on brain volumes, identifies genetic loci, and develops polygenic scores with cross-ancestry predictive ability and causal links to neuropsychiatric disorders.

Smaug regulates germ plasm synthesis and primordial germ cell number in Drosophila embryos by repressing the oskar and bruno 1 mRNAs

The paper identifies Smaug's role in repressing osk and bru1 mRNAs to regulate germ plasm synthesis and PGC number in Drosophila embryos.

Dopamine and schizophrenia from bench to bedside: Discovery of a striatal co-expression risk gene set that predicts in vivo measures of striatal function.

The paper identifies a striatal gene set linked to schizophrenia risk that predicts in vivo dopamine synthesis and striatal activation in neurotypical and patient cohorts.

A Biologically Interpretable Graph Convolutional Network to Link Genetic Risk Pathways and Neuroimaging Phenotypes of Disease

This paper introduces a graph convolutional network that links genetic risk pathways with neuroimaging phenotypes in schizophrenia, achieving better classification performance than existing methods.

The genetic architecture of the human cerebral cortex

The paper identifies genetic loci associated with human cortical structure and finds genetic correlations with neuropsychiatric disorders.

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

The paper identifies 25 genetic loci associated with subcortical brain structure volumes in over 40,000 individuals, revealing novel biology and potential drug targets.