Chaini Konwar

Prenatal diet buffers infant epigenetic changes linked to pollution and transient wheeze

This study examines how prenatal air pollution exposure affects DNA methylation in cord blood and its link to childhood wheeze, finding some epigenetic changes are partially buffered by maternal diet.

RAMEN: Dissecting individual, additive and interactive gene-environment contributions to DNA methylome variability in cord blood

RAMEN dissects gene-environment contributions to DNA methylome variability in cord blood, finding genetics explains the largest proportion of DNAme variance.

Accounting for differences between Infinium MethylationEPIC v2 and v1 in DNA methylation-based tools

This study examines differences between Infinium MethylationEPIC v1 and v2, showing high array-level concordance but probe-level variation, and recommends accounting for version differences in analyses.

Advancing Pediatric and Longitudinal DNA Methylation Studies with CellsPickMe, an Integrated Blood Cell Deconvolution Method

CellsPickMe improves blood cell deconvolution in longitudinal DNA methylation studies by integrating cord and adult references, enhancing accuracy across developmental stages.

Profiling placental DNA methylation associated with maternal SSRI treatment during pregnancy

This study examines DNA methylation changes in placental samples from mothers treated with SSRIs during pregnancy and finds no significant differentially methylated CpGs.

A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta

The paper identifies sex-associated differentially methylated CpGs in term placenta DNA using two cohorts and links them to maternal age and birthweight.