ImmunologyScientific ReportsPeer-reviewed
Mast Cell Specific Cyp11a1 Deficiency Promotes T Cell Mediated Immunity and Suppresses Tumour Metastasis in a Mouse Model of Melanoma
M. Abdul Alim, Katie Butcher, Hosni A.M. Hussein
This study shows that mast cell-specific Cyp11a1 deficiency reduces melanoma metastasis by enhancing T cell immunity and suppressing mast cell-derived steroid effects.
DOI 10.1038/s41598-026-56344-5