Splenic MARCO+ marginal zone macrophages regulate rapid production of MCP-1 and KC but are dispensable for alloantibody generation in response to stored RBCs in a murine model.
Abhinav Arneja, Juan E. Salazar, Jelena Medved…·Chance John Luckey
This study shows splenic MARCO+ marginal zone macrophages (MZMs) enhance cytokine production but are not required for anti-RBC alloantibody generation after stored RBC transfusion in mice.