BiochemistrybioRxivPreprint
AMPK activation promotes transcriptional activation of TFEB through its dephosphorylation
Florentina Negoita, Conchita Fraguas Bringas, Kristina Hellberg…·Kei Sakamoto
The paper shows that AMPK activation leads to dephosphorylation of TFEB's C-terminal sites, promoting its transcriptional activation, and that AMPK is not required for mTORC1-mediated TFEB activation.
DOI 10.1101/2024.10.22.619589