Molecular BiologyMolecular PsychiatryPeer-reviewed
Role of FMRP in rapid antidepressant effects and synapse regulation
Chelcie F. Heaney, Sanjeev V. Namjoshi, Ayse Uneri…·Kimberly F. Raab‐Graham
This study shows that FMRP is required for the rapid antidepressant effects of Ro-25-6981 and that its regulation by mTORC1 and GABABR activity influences synapse formation and treatment outcomes in FXS models.
8 citations