MicrobiologyCell chemical biologyPeer-reviewed
Exploiting Vitamin B6 Dependency: BVL3572S Inhibits HisC and AlaA to Kill Mycobacterium tuberculosis
Zainab Edoo, Astrid Lenne, Camille Grosse…·Alain R. Baulard
This paper identifies BVL3572S as a compound that inhibits HisC and AlaA in Mtb, causing metabolic stress and showing synergy with existing drugs.
DOI 10.1016/j.chembiol.2026.07.008