ADAM17 regulates hepatic DNA damage repair and tumour formation
Manuel Reichert, Birgit Halwachs, Julia Bolik, Anke Senftleben, Freia Krause, Luisa Conrady, Renate Bauer, Jacob Rachmilewitz, Jutta Horejs‐Hoeck, Stefan Rose‐John, Dirk Schmidt‐Arras
This study shows ADAM17 on myeloid cells drives hepatic DNA damage repair and tumour formation in HCC, suggesting it as a therapeutic target.
bioRxiv · Jul 30, 2024 · PreprintCancer Biology