Hassan Hashimi

This study uses complexome profiling to reveal new interactions and structural insights into the mitochondrial respiratory chain of Trypanosoma brucei.

This study shows that MICOS assembles on non-respiring mitochondrial precursor cristae in trypanosomes and identifies new associated proteins.

The paper shows that Euglenozoa replaced the Mic60 subunit of the MICOS complex with two mitofilin-containing proteins, Mic34 and Mic40, which have distinct structural and functional properties.

The paper identifies TbKifX2A and TbPH1 as proteins interacting at the trypanosomal microtubule quartet, showing their localization and functional roles in maintaining flagellar pocket structure.