Amitabha Nandi

The paper investigates yolk-cytoplasm segregation in Drosophila embryos and identifies microtubule dynamics as the primary driver of this process.

This study proposes a model of spatially varying diffusion to explain how the Bicoid gradient scales with embryo size in Drosophila, showing that gradient scaling arises from spatial heterogeneity rather than nuclear trapping.

The paper uses photoactivation to study how cyto-architecture constrains the spread of cytoplasmic and tubulin molecules in Drosophila embryos, showing that tubulin gradients are more restricted by microtubules and plasma membrane structure.