James Ashley

Structural insights into wiring specificity in the neuromuscular system through the Beat-Side complex

The paper reports the first structure of the Beat-Side complex and shows its role in motor neuron connectivity in Drosophila.

Neuronal wiring receptors Dprs and DIPs are GPI anchored and this modification contributes to their cell surface organization

This study shows that Drosophila Dpr and DIP proteins are GPI anchored, and this modification is necessary for their cell surface organization and function.

Glial Draper signaling triggers cross-neuron plasticity in bystander neurons after neuronal cell death

Systematic expression profiling of dprs and DIPs reveals cell surface codes in Drosophila larval peripheral neurons

The paper systematically profiles dprs and DIPs expression in Drosophila larval neurons to identify cell surface codes involved in synaptic recognition.

Structural and functional synaptic plasticity induced by convergent synapse loss requires co-innervation in the Drosophila neuromuscular circuit

The paper investigates how the loss of one convergent synaptic input affects the structural and functional plasticity of adjacent inputs in Drosophila neuromuscular circuits, finding that co-innervation is necessary for robust compensation.

Transsynaptic interactions between IgSF proteins DIP-α and Dpr10 are required for motor neuron targeting specificity in Drosophila