Jia‐Ming Chang

GBactPro improves cross-species bacterial promoter prediction using element-resolved promoter definitions, achieving high AUROC across multiple species and outperforming existing predictors.

This paper reports on the fourth CAFA challenge, showing improvements in Gene Ontology term prediction but highlighting challenges in new evaluation settings.

HiCPEP estimates chromatin compartment PC1 from Hi-C data without eigenvector decomposition, achieving efficiency and accuracy comparable to standard PCA methods.

The paper identifies hundreds of Drosophila chromatin insulator elements dependent on Cp190 and CTCF by analyzing genomic contacts, transcriptomes, and protein binding in deficient cells.