The C-terminal domain of Hsp70 is responsible for paralog-specific regulation of ribonucleotide reductase
Laura E. Knighton, Nitika Nitika, Siddhi Omkar, Andrew W. Truman
The paper shows that the C-terminal domain of Hsp70 paralogs Ssa3 and Ssa4 specifically regulates ribonucleotide reductase, affecting DNA damage resistance and RNR subunit stability.
PLoS Genetics · Apr 13, 2022Peer-reviewedGenetics