Chemical proteomic profiling of protein dopaminylation in colorectal cancer cells
Nan Zhang, Shuaixin Gao, Haidong Peng, Jinghua Wu, Huapeng Li, Connor Gibson, Sophia Wu, Jiangjiang Zhu, Qingfei Zheng
The paper identifies 425 dopaminylated proteins in colorectal cancer cells using a chemical probe, revealing their involvement in nucleic acid metabolism and transcription, and suggests targeting protein dopaminylation as a potential anti-cancer strategy.
Journal of Proteome Research · Jun 5, 2024Peer-reviewedBiochemistry