The crystal structure of the activin B:Fst288 complex and computational insights into the broad antagonistic activity and specificity of follistatin
Lucija Hok, Ryan G. Walker, James Anthony Howard, Melissa M. Gouge, Eleanor M. Mast, Chandramohan Kattamuri, Erich J. Goebel, Thomas B. Thompson
The paper solves the crystal structure of the ActB:Fst288 complex and uses computational analysis to explain Fst288's broad antagonistic activity and specificity for activins.
Journal of Biological Chemistry · Aug 17, 2026Peer-reviewedMolecular Biology