Author

Edmund Leach

University of CincinnatiORCID 0009-0009-0397-6002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Thomas B. ThompsoniD· 2 shared Alena S Bruening· 1 shared David PépiniD· 1 shared Eleanor M. MastiD· 1 shared James Anthony HowardiD· 1 shared Kaitlin N. HartiD· 1 shared Lucija HokiD· 1 shared Nathaniel J SanfordiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Thomas B. ThompsonORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 1, 2024

Structural Basis of Non-Latent Signaling by the Anti-Mullerian Hormone Procomplex

James Anthony Howard, Lucija Hok, Richard L. Cate…·Thomas B. Thompson

This study reveals the structural basis of AMH procomplex signaling, showing how the prodomain maintains activity through a unique conformational mechanism.

1 citation

experimental assay

𝕏 PostBluesky

Molecular BiologyJournal of Biological ChemistryPeer-reviewedNov 9, 2023

Characterization of erythroferrone oligomerization and its impact on BMP antagonism

Eleanor M. Mast, Edmund Leach, Thomas B. Thompson

This study investigates how erythroferrone (ERFE) oligomerization affects its ability to inhibit BMP ligands, identifying a critical ligand binding domain essential for BMP antagonism.

9 citations

humanproteomics

𝕏 PostBluesky