Erlin1/2 Complex is a Dynamic Scaffold for Membrane Protein Sequestration and Microdomain Assembly on the Endoplasmic Reticulum
Lu Yan, Zhihong H. Xu, Yuanhang Yao, Xiaoting Wang, Yonglun Wang, Chengying Ma, Ningning Li, Xiaowei Chen, Ning Gao
This study determines the cryo-EM structure of the erlin1/2 complex and reveals its role in sequestering membrane proteins and organizing functional microdomains on the ER.
bioRxiv · Jun 14, 2025 · PreprintBiophysics