Author

José Luis Garrido-Huarte

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-6770-0170Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Amparo Pascual‐AhuiriD· 2 shared Josep Fita‐TorróiD· 2 shared Markus ProftiD· 2 shared Agnès H. MicheliD· 1 shared Benoı̂t KornmanniD· 1 shared Lucía López-Gil· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersMolecular Biology

Amparo Pascual‐AhuirORCID

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2 papers

Recent·Most cited

Lipid-Mediated Control of ER Function During Apoptosis

José Luis Garrido-Huarte, Josep Fita‐Torró, Amparo Pascual‐Ahuir, Markus Proft

This study identifies Fmp52 as an essential factor for detoxifying sphingolipid-derived fatty aldehyde t-2-hex in yeast, linking lipid metabolism to ER proteostasis and apoptosis.

bioRxiv · Dec 1, 2025 · PreprintMolecular Biology

Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid

Josep Fita‐Torró, José Luis Garrido-Huarte, Lucía López-Gil, Agnès H. Michel, Benoı̂t Kornmann, Amparo Pascual‐Ahuir, Markus Proft

The paper investigates how the pro-apoptotic lipid t-2-hex disrupts mitochondrial protein import and proteostasis in yeast, identifying key mechanisms and targets.

eLife · May 30, 2025Peer-reviewedMolecular Biology