Author

João Victor da Silva Guerra

Brazilian Center for Research in Energy and MaterialsORCID 0000-0002-6800-4425Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:graph neural network· 1 Research Focus:protein design· 1 Approach:statistical model· 1

Frequent Co-Authors

Helder Veras Ribeiro FilhoiD· 2 shared Brian G. PierceiD· 1 shared Carlos Daniel Marques Santos SimõesiD· 1 shared Gabriel Ernesto JaraiD· 1 shared José Geraldo de Carvalho PereiraiD· 1 shared Melyssa CheungiD· 1 shared Nathaniel R. FelbingeriD· 1 shared Paulo Sérgio Lopes de OliveiraiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Helder Veras Ribeiro FilhoORCID

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2 papers

Recent·Most cited

BioinformaticsBriefings in BioinformaticsPeer-reviewedSep 1, 2026

MHCXGraph: A Graph-Based approach to detecting T cell receptor cross-reactivity

Carlos Daniel Marques Santos Simões, Rocío Lucía Beatriz Riveros Maidana, Samuel Chagas de Assis…·Helder Veras Ribeiro Filho

MHCXGraph identifies conserved structural regions in pMHC complexes to detect T cell cross-reactivity using graph-based analysis.

DOI 10.1093/bib/bbag555

protein structuregraph neural network

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BioinformaticsPLoS Computational BiologyPeer-reviewedSep 30, 2024

Exploring the Potential of Structure-Based Deep Learning Approaches for T cell Receptor Design

Helder Veras Ribeiro Filho, Gabriel Ernesto Jara, João Victor da Silva Guerra…·Paulo Sérgio Lopes de Oliveira

This study evaluates two deep learning methods for designing T cell receptors by comparing their performance to physics-based approaches in binding target antigens.

9 citations

protein structuredeep learning

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