Helder Veras Ribeiro Filho

MHCXGraph identifies conserved structural regions in pMHC complexes to detect T cell cross-reactivity using graph-based analysis.

This study uses NMR and modeling to determine how MinC interacts with FtsZ, revealing that MinC caps FtsZ filaments to inhibit Z-ring formation.

The paper determines crystal structures of a TCR complex with NRAS neoantigens and uses AlphaFold to model these complexes, showing varying success across different implementations.

This study evaluates two deep learning methods for designing T cell receptors by comparing their performance to physics-based approaches in binding target antigens.