Direct Reconstruction of Gene Regulatory Networks underlying Cellular state Transitions without Pseudo-time Inference
Ruosi Wan, Yuhao Zhang, Yongli Peng, Feng Tian, Ge Gao, Fuchou Tang, Xiaoliang S. Xie, Jinzhu Jia, Hao Ge
This paper introduces COSLIR, a method to directly reconstruct gene regulatory networks from time-stamped single-cell data without pseudo-time inference, showing good performance on real datasets.
bioRxiv · May 12, 2021 · PreprintBioinformatics