Molecular BiologybioRxivPreprint
MED1 IDR acetylation reorganizes the transcription preinitiation complex, rewires 3D chromatin interactions and reprograms gene expression
Ran Lin, Robert G. Roeder, Douglas Barrows…·Zhiguo Zhang
This study shows that acetylation of MED1's IDR affects PIC assembly, chromatin organization, and gene expression in ER+ breast cancer cells.