Cell BiologybioRxivPreprint
Splicing factor SRSF1 is a pH-stat to restore nucleolar integrity and function
Suibin Ma, Jierui Guo, Xiang Zhan…·Bo Wang
This study identifies SRSF1 as a pH-regulating factor that maintains nucleolar integrity by alkalizing the nucleolar microenvironment through its RS domain.
DOI 10.1101/2025.04.12.648491