Tobias Lynge Madsen

Male obesity causes adipose mitochondrial dysfunction in F1 progeny via a let-7-DICER axis.

This study shows that male obesity affects adipose mitochondrial function in offspring via the let-7-DICER axis, with reversible effects observed in both mice and human semen.

Unique genomic features and deeply-conserved functions of long non-coding RNAs in the Cancer LncRNA Census (CLC)

The paper introduces the Cancer LncRNA Census (CLC), a curated resource of lncRNAs with causative roles in cancer, and shows their genomic and evolutionary features.

EBADIMEX: An empirical Bayes approach to detect joint differential expression and methylation and to classify samples

EBADIMEX detects joint differential expression and methylation and classifies cancer samples using empirical Bayes methods and moderated tests.

Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

The paper identifies and characterizes coding and non-coding driver mutations across 2,500 cancer genomes, revealing new candidates and questioning previous findings.