Signe Skog

IGS38, a lncRNA from the human rDNA intergenic spacer, regulates rRNA transcription by altering rDNA chromatin organisation and activating the transcription machinery

This paper identifies IGS38, a lncRNA that enhances rRNA transcription by altering chromatin structure and promoting RNA polymerase I promoter escape.

Male obesity causes adipose mitochondrial dysfunction in F1 progeny via a let-7-DICER axis.

This study shows that male obesity affects adipose mitochondrial function in offspring via the let-7-DICER axis, with reversible effects observed in both mice and human semen.

Early embryonic heat shock induces long-term epigenetic memory by affecting the transition to zygotic independence

The paper investigates how early embryonic heat shock in Drosophila affects sncRNA expression and long-term epigenetic memory through miRNA and Elba1 interactions.

Nutritional dependence of sperm mitochondrial metabolism and small RNA biogenesis

This study shows diet rapidly alters sperm proteomic and small RNA profiles in Drosophila, with mitochondrial ROS and miRNA changes linked to dietary sugar.

Seqpac: A New Framework for small RNA analysis in R using Sequence-Based Counts

Seqpac provides an R-based framework for analyzing small RNA sequencing data, improving transparency and flexibility through sequence-based counting and group analysis.

5'XP sRNA-seq: Efficient Identification of Transcripts With and Without 5' Phosphorylation Reveals Evolutionary Conserved Small RNA

The paper introduces 5XP-seq, a method to identify 5' phosphorylated and non-phosphorylated sRNAs, revealing evolutionary conserved small RNA species across species.