Jan‐Wilhelm Kornfeld

EctoShed is a gene delivery platform that enables expression of both membrane-bound and soluble proteoforms in adipocytes, revealing their functional roles in metabolic regulation.

The paper examines how dietary sulfur amino acid restriction and cold exposure affect energy expenditure and transcriptomic responses in different adipose tissues of male mice.

This study shows that male obesity affects adipose mitochondrial function in offspring via the let-7-DICER axis, with reversible effects observed in both mice and human semen.

This study shows that ACBP is not essential for adipose tissue function or systemic energy metabolism in mice, as knockout mice show no significant metabolic changes.

The paper benchmarks ONT long-read sequencing against Illumina short-read sequencing in cold-activated BAT, finding ONT superior for transcriptome reassembly but less powerful for differential expression analysis.

The paper investigates the role of the adipose tissue-specific lncRNA Gm15551 in BAT activation through transcriptional profiling and phenotyping, finding no significant effect on adipocyte function.