Mechanistic studies of PFKFB2 reveals a novel inhibitor of its kinase activity
Craig A. Eyster, Satoshi Matsuzaki, Atul Pranay, Jennifer R. Giorgione, Anna Faakye, Mostafa H. Ahmed, Kenneth Michael Humphries
The paper identifies and validates a new inhibitor, B2, of PFKFB2 kinase activity through enzymatic assays and metabolic profiling in A-498 cells.
PLoS ONE · May 22, 2025Peer-reviewedBiochemistry