Input dose differentiation by NF-κB
Minjun Son, Andrew Wang, Hsiung‐Lin Tu, Marie Oliver Metzig, Parthiv Patel, Kabir B. Husain, Jing Lin, Arvind Murugan, Alexander Hoffmann, Savaş Tay
The paper shows NF-κB differentiates cytokine input doses by using negative feedback loops to track changes in concentration rather than absolute levels.
bioRxiv · Sep 4, 2019 · PreprintSystems Biology