Author

Marie Oliver Metzig

University of California, Los AngelesORCID 0000-0003-1182-8121Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander HoffmanniD· 3 shared Andrew WangiD· 1 shared Arvind MuruganiD· 1 shared Brooks E. Taylor· 1 shared Carlos F. LopeziD· 1 shared Geena V. IldefonsoiD· 1 shared Hsiung‐Lin TuiD· 1 shared Jing LiniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersSystems Biology

Alexander HoffmannORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintFeb 25, 2022

Distinct execution modes of a biochemical necroptosis model explain cell type-specific responses and variability to cell-death cues

Geena V. Ildefonso, Marie Oliver Metzig, Alexander Hoffmann…·Carlos F. Lopez

2 citations

proteomicsstatistical model

𝕏 PostBluesky

Systems BiologyMolecular Systems BiologyPeer-reviewedDec 1, 2020

An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions

Marie Oliver Metzig, Ying Tang, Simon A. Mitchell…·Alexander Hoffmann

The paper identifies an incoherent feedforward loop involving NFκB/RelA and A20 that determines TNF-induced necroptosis decisions based on dynamic signaling.

31 citations

experimental assay

𝕏 PostBluesky

Systems BiologybioRxivPreprintSep 4, 2019

Input dose differentiation by NF-κB

Minjun Son, Andrew Wang, Hsiung‐Lin Tu…·Savaş Tay

The paper shows NF-κB differentiates cytokine input doses by using negative feedback loops to track changes in concentration rather than absolute levels.

1 citation

statistical model

𝕏 PostBluesky