Piezo1 is a mechanosensor of soft matrix viscoelasticity
Mariana Azevedo Gonzalez‐Oliva, Giuseppe Ciccone, Gotthold Fläschner, Jiajun Luo, Jonah L. Voigt, Patrizia Romani, Paul G. Genever, Oana Dobre, Sirio Dupont, Massimo Vassalli, Pere Roca‐Cusachs, Manuel Salmerón‐Sánchez
The paper shows Piezo1 senses viscoelasticity in soft ECMs and identifies transcriptomic changes in MSCs in response to matrix properties and Piezo1 activity.
Nature Communications · Oct 15, 2025Peer-reviewedBiophysics