Paul G. Genever

Mechanoscribed Xolography for Multiscale Mechanical Patterning of Cell-laden Hydrogels

This paper introduces a 3D bioprinting technique called Mechanoscribed Xolography to create cell-laden hydrogels with controlled mechanical heterogeneity and monitors their evolution over time.

Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype

This study compares EV bioactivity and clinical utility from two clonal MSC subtypes, finding Y201 EVs show enhanced proliferation effects and in vivo efficacy compared to Y202 EVs.

Piezo1 is a mechanosensor of soft matrix viscoelasticity

The paper shows Piezo1 senses viscoelasticity in soft ECMs and identifies transcriptomic changes in MSCs in response to matrix properties and Piezo1 activity.