Author

Gotthold Fläschner

Barcelona Institute of Science and TechnologyORCID 0000-0001-6707-6905Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

Pere Roca‐CusachsiD· 2 shared Daniel J. MülleriD· 1 shared Eleni DalakaiD· 1 shared Giuseppe CicconeiD· 1 shared Ilia PlatzmaniD· 1 shared Javier Casares-AriasiD· 1 shared Jiajun LuoiD· 1 shared Jonah L. VoigtiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

Pere Roca‐CusachsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 15, 2026

α5β1 and αvβ3 integrins employ two distinct adhesion strengthening modes to respond to fibronectin stiffness within seconds of initiating adhesion

Nico Strohmeyer, Upnishad Sharma, Michele M. Nava…·Daniel J. Müller

This study shows fibroblasts use two distinct adhesion strengthening modes, slow and fast, in response to fibronectin stiffness, with fast mode dependent on myosin II and signaling hub components.

DOI 10.64898/2026.07.09.737593

humanexperimental assay

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedOct 15, 2025

Piezo1 is a mechanosensor of soft matrix viscoelasticity

Mariana Azevedo Gonzalez‐Oliva, Giuseppe Ciccone, Gotthold Fläschner…·Manuel Salmerón‐Sánchez

The paper shows Piezo1 senses viscoelasticity in soft ECMs and identifies transcriptomic changes in MSCs in response to matrix properties and Piezo1 activity.

36 citationstop 1%

bulk RNA-seqexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivPreprintJul 21, 2025

Mechanically Tunable DNA Hydrogel Microparticles for 3D Cellular Systems

Tobias Walther, Eleni Dalaka, Gotthold Fläschner…·Kerstin Göpfrich

This paper introduces DNA-based hydrogel microparticles with tunable mechanical properties for 3D cellular systems, showing they can be remodeled by fibroblast spheroids based on their stiffness.

DOI 10.1101/2025.07.21.665473

experimental assaycell type annotation

𝕏 PostBluesky